Friday, June 8, 2012

Oxidative Stress, Inflamation and Dry Eye Syndrome

We have long suspected that stress at work can create chronic dry eyes.

Finally a body of scientific evidence that links stress and chronic dry eye syndrome.
Here is an abstract from an article published in Cornea: October 2009 - Volume 28 - Issue 11 - pp S70-S74
There is a growing body of evidence to suggest that oxidative stress may be involved in at least the propagation of cellular injury that leads to eye pathology in various conditions including conjunctivochalasis, dry eye disease, age-related macular degeneration, and UV light-induced and tobacco smoke-induced ocular surface epithelial damage. Oxidative stress is biologically relevant in vivo and intimately linked with an integrated series of cellular events. Interaction between these various components is not necessarily a cascade but might be a cycle of events, of which oxidative stress is a major component. Inhibition of oxidative stress therapeutically might act to break the cycle of cell death. The creation of numerous cell and animal models that selectively target the effects of oxidative stress and inflammation to the specifically affected eye region in these diseases has greatly advanced our understanding of the involvement of oxidative stress in eye disease.

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1 comment:

  1. Daily Stress has long been suspected to cause Chronic Dry Eye Syndrome. See what else this can cause in Eye Diseases