Friday, December 21, 2012

Autologous Serum for Chronic Dry Eyes- Drawback and Benefits

Many of our dry eye patients are on autologous serum drops and still have severe chronic dry eye symptoms.  This is because treating dry eyes from the surface is insufficient for chronic dry eye relief because the tear secretion glands are under active after repeated inflammation which causes cellular functions to be suppressed

Read on, TheraLife can help- Revive your own natural tears now!

The use of autologous serum (AS) for treating ocular surface disorders dates back to at least the 1970s when it was used via a mobile ocular perfusion pump to treat ocular alkali burns.1  AS was described as a tear substitute in 1984 in the journal Arthritis and Rheumatism2 . The use of AS for the treatment of ocular surface disorders did not gain popularity until the late 1990s.3  The most common uses include the treatment of dry eyes4.   AS has also been suggested to  treat neurotrophic keratopathy- a recurrent corneal erosion6 and superior limbic keratoconjunctivitis (inflammation of the superior bulbar conjunctiva).

Aotologous Serum for Dry Eye

One of the aplications for AS is for severe dry eyes.  The reason being artificial tears lack essential tear components such as growth factors, vitamins, and immunoglobulins.8  Human serum contains substances such as epidermal growth factor, vitamin A, fibronectin and cytokines normally found in tears. These factors are important for maintaining a healthy corneal and conjunctival epithelium.10

Drawbacks of Serum Eye Drops Treatment

The drawbacks include:
1.  Infections - Since AS preparation is a body fluid, it is able to transmit infections.11  This includes viral infections such as hepatitis B and C , HIV (AIDS).

2.  Cost - Frequent blood extractions from the patient requiring prolonged treatment. Patients who need to use AS eye drops for an extended period of time will need to provide blood samples at least every three months.  AS eye drop therapy can be expensive. Daily cost could be 45-10 dollars.  Patients generally have to pay out-of-pocket for the AS eye drops because the majority of insurance carriers do not cover this treatment.  

3. Microbial Infections - AS contains no preservatives, which avoids the risk of preservative toxicity, however there is a potential risk of inducing infections because of microbial contamination of the dropper bottle.4


Autologous serum drops can be helpful.  However, when autologous serum, puntal plugs and prescription eye drops do not work.  Look to TheraLife for help.

Why TheraLife Eye?
Prolonged inflammation resulted from chronic dry eyes shut down normal cellular functions of tear secretion glands.  TheraLife revitalize the normal eye functions intracellularly to restore normal function.  It is not an eye drops, it is a capsule.


To learn more.
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This article is abstracted from Optometric Management Sept, 2012.

REFERENCES
1. Ralph RA, Doane MG, Dohlman CH. Clinical experience with a mobile ocular perfusion pump. Arch Ophthalmol 1975; 93 (10): 1039-1043.
2. Fox RI, Chan R, Michelson JB, et al. Beneficial effects of artificial tears made with autologous serum in patients with keratoconjunctivitis sicca. Arthritis Rheum 1984; 27 (4): 459-461.
3. Jeng BH. Use of autologous serum in the treatment of ocular surface disorders. Arch Ophthalmol 2011; 129 (12): 1610-1612.
4. Lee GA, Chen SX. Autologous serum in the management of recalcitrant dry eye syndrome. Clin Experiment Ophthalmol 2008; 36 (2): 119-122.
5. Matsuoto Y, Dogru M, Goto E, et al. Autologous serum application in the treatment of neurotrophic keratopathy. Ophthalmology 2004; 111 (6): 1115-1120.
6. delCastillo JMB, de las Casa JMM, Sardina RC, et al. Treatment of recurrent corneal erosions using autologous serum. Cornea 2007; 21 (8): 781-783.
7. Goto E, Shimmura S, Shimazaki J, et al. Treatment of superior limbic keratoconjunctivitis by application of autologous serum. Cornea 2001; 20 (8): 807-810.
8. Quinto GG, Campos M, Behrens A. Autologous serum for ocular surface diseases. Arq Bras Oftalmol 2008; 71 (6 Suppl): 47-54.
9. Lopez-Garcia JS, Garcia-Lozano I, Rivas L, et al. Use of autologous serum in ophthalmic practice. Arch Soc Esp Oftalmol 2007; 82 (1): 9-20.
10. Koffler BH. Autologous serum therapy of the ocular surface with novel delivery by platelet concentrate gel. Ocul Surf 2006; 4(4): 188-195.
11. Geerling G, Maclennan S, Hartwig D. Autologous serum eye drops for ocular surface disorders. Br J Ophthalmol 2004 (88): 1467-1474.
12. Weisbach V, DietrichT, Kruse FE, et al. HIV and hepatitis B/C infections in patients donating blood for use as autologous serum eye drops. Br J Ophthalmol 2007; 91 (12): 1724-1725.
13. Eberle J, Habermann J, Gurtler IG. HIV-1 infection transmitted by serum droplets into the eye: a case report. AIDS 2000; 14: 206-207.

Tuesday, December 4, 2012

Severe Chronic Dry Eyes with Eye Ulcer- Complete Recovery with TheraLife Eye

It is known that chronic dry eyes left untreated can cause cornea damage, vision impairment and potentially blindness.  The following personal story only illustrate the fact that even for severe chronic dry eyes with eye ulcer, TheraLife Eye is able to restore tear glands to secrete balanced natural tears from your own body.

Severe dry eyes with eye ulcer. Relief by TheraLife Eye from Australia
"Over the last 21 months since we made our first purchase from TheraLife Inc, my wife has had amazing success with your “TheraLife Eye Enhanced”. No other product has come anywhere near to curing her dry eye. Before starting your recommended dosage of “TheraLife Eye Enhanced” and Omega-3 Fish Oil, her dry eye was so bad that she had a very painful ulcer in her eye. As recommended by you, she completely stopped using all other temporarily expedient, proscribed products. Although she understands that she must continue to take a maintenance dosage for the rest of her life, your “TheraLife Eye Enhanced” has completely removed all her eye discomfort and all she has to do if she detects a slight return of mild symptoms, is to temporarily increase dosage for a day or so."  R M, Australia,


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Friday, November 30, 2012

The Best Wraparound Sunglasses for Dry Eyes

Most people with chronic dry eye syndrome are affected by sun, wind and glare.

We get many questions regarding the best sunglasses to wear to help protect eyes from exposure to sensitive elements and potential damage due to long-term exposure to sunlight. Excessive exposure to UV radiation and blue light from the sun can cause cataracts, contribute to the onset of retinal diseases such as macular degeneration, and cause skin cancer in the sensitive tissue surrounding one's eyes. Radiation damage can even occur on cloudy days.

We recommend 100% UVA/UVB protecting wraparound glasses. The best lens color is amber, which also neutralizes blue light. Brown is the next best color.

Cheaper glasses may have a coating to block out UV light that can rub off overtime. Many people think it is the tint that helps protect one's eyes, but it is actually the UV filter on, or in, the lens. So, if the filtering coating wears off, a dark lens actually increases pupil dilation, allowing more light to enter the eyes.

Relief Your Dry Eyes with TheraLife Eye
TheraLife Eye is a capsule.  It is not an eye drops.  TheraLife Eye revitalize your dry eyes intra-cellularly to secrete your own balanced tears.  Clinically proven to work in 80% first time users.  Get relief today.


To learn more how TheraLife Eye works.
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Call and talk to a doctor toll free 1-877-917-1989 US and Canada. International (650) 949-6080
email inquiries to: info@theralife.com
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Tuesday, November 27, 2012

Coping with Depression Caused by Chronic Dry Eyes

It has been well documented that chronic dry eyes cause depression- see another TheraLife blog here.   Maybe your dry eyes hurt so much that all you can think of all day and all night is how much pain you are feeling.  Do you get up in the middle of the night to put eye drops in your eyes?
Does sadness overwhelm you at times, leaving you unable to enjoy the people and activities in your life?

When your emotions cloud your outlook, interfere with your relationships or affect the way you sleep at night and function during the day, you may be suffering from depression or an anxiety disorder.
You're not the only one who feels sad or worried when you have chronic dry eyes.  at times. It's normal.  Chronic dry eyes affect a person’s quality of life.  It's perfectly natural for you to respond to the ups and downs we all experience with elation or fear.

It's common, and occasionally even helpful, for you to react to life's stresses, challenges and dangers with anxiety.
  • What's NOT perfectly natural is when those feelings persist long after the event or condition that triggered them.
  • What's NOT normal and expected is when those feelings seem to come at you from nowhere, appearing even in the absence of obvious external triggers.
  • What's certainly NOT helpful is feeling the weight of your emotions so heavily that they interfere with sleep, prevent you from performing daily activities or arouse concern in the people who care about you.
In its milder forms, depression or anxiety can make it difficult to even get yourself out of bed each morning and to go through the motions of your daily activities. Fatigue, inertia, feelings of sadness and recurring fears can hover like a rain cloud over your life.

In its more severe forms, a depression or an anxiety disorder can immobilize you, sabotage your relationships, trigger feelings of helplessness and self-destructive behavior, and perhaps even turn your thoughts to suicide.
You DON'T have to suffer this way
The most important thing for you is to permanently resolve this issue of chronic dry eyes so your life can get back to normal.   


TheraLife Can Help
In a clinical trial, TheraLife Eye relieved dry eye symptoms in 80% of the dry eye sufferers.  TheraLife Eye is a capsules that treats dry eyes from inside out, unlike most of the other dry eye relief today that is based on drops, treating the surface of the eye ball.  It has been shown that frequent use of eye drops make eyes drier.  Take a different approach now.


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Call and talk to a doctor 1-877-917-1989 US and Canada.  International (650) 949-6080
Send inquiries to : info@theralife.com
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Tuesday, November 20, 2012

Meibomian Gland Dysfunction- How TheraLife Can Help

The primary function of meibomian glands is to secret lipids, the thickening agent for tears.  In chronic dry eye syndrome, meibomian glands play an important part of  dry eye relief.  the inability to thicken tears lead to evaporative dry eyes.  Blepharitis (eye lid abnormalities and infections), Rosacea often concur with Meibomian Gland Dysfunction (MGD) making it one of the most difficult dry eye conditions to treat.  Assessment and treatment of meibomian gland disease is often a necessary step in successful dry eye treatment.

How to look for  Meibomian Gland Dysfunction

Normal meibum is thin with clear liquid which is expressed very easily.  With various stages of MGD, the meibum becomes thicker, (see photo above) and the expressed liquid becomes thicker, granular and some time in clumps and the liquid become opague.  The expressing meibum can be very difficult.

Often MGD is accompanied by lots of inflammation - on the eye lid, in the eye.  In most cases, MGD is accompanied also by tear volume in-sufficiencies (Lacrimal Gland). Thus setting up a situation where dry eyes cause inflammation and the inflammation causes the tear secretion glands to shut down.

Certain drugs can cause MGD, especially drugs to dry up acne - such as Accutane, antihistamines used in allergy treatments.


Treatment of Meibomian Gland Dysfunction

Typical treatments for MGD includes:
1. Wet hot compresses - twice a day, each time 10 minutes to unclog the meibomian glands
2. Eye lids cleaning daily to minimize eye infections
3. Oral Antibiotcis - Doxycycline or Azithromycin daily
4. Steroid eye drops - such as Lotamax or PredForte to calm down inflammation during a flare. Steroid eye drops are limited to one month since long term use may result in kidney and liver damages.

How can TheraLife help?

TheraLife Eye is formulated to revitalize all the tear secretion glands, including meibomian glands, lacrimal glands to get sustainable long lasting relief.  TheraLife Eye is used along with the procedures described above for speedy recovery and long term maintenance.


To learn more
Video
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Call and talk to a doctor toll free 1-877-917-1989
International ( 650) 949-6080
email to: info@theralife.com
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photo curtesy of Gary N. Foulks MD, FACS.