New Research on Dry Eyes & Allergies in Children
Allergies and Dry Eye Disease often concur. Here is a research
study that supports this finding. Tear film instabilities result in
evaporative dry eyes.
Evaluation of the Tear Film Instability in Children with Allergic Diseases
CONTEXT: The presence of dry eye syndrome (DES) in ocular allergic
diseases was evaluated in several studies. Despite this, little exists
about the tear film instability in atopic children including patients
with allergic rhinitis (AR), allergic conjunctivitis (AC) and asthma.
This is a study which presents intriguing findings regarding the
relationship of tear film instability with clinical aspects in atopic
children.
OBJECTIVE: To determine the tear film instability in children with AR, AC and asthma.
MATERIALS AND METHODS: One hundred and thirty-five consecutive children
with AR, AC and asthma as study group and 45 children without any
systemic and ocular abnormality as control group were included in the
study. Skin prick tests, measurement of tear film breakup time (TFBUT),
serum immunoglobulin E and eosinophil counts were performed in all
patients. Also four subgroups of patients were designated as AR group
(Group I), AC group (Group II), asthma group (Group III) and control
group (Group IV).
RESULTS: Socio-demographic characteristics were similar except for family atopy between the groups (p > 0.05). The mean TFBUT was significantly lower in the study group (15.5 ± 4.4 s) than the control group (18.4 ± 2.9 s; p 0.000). Also, there was no significant differences in the percentage of the patients who had TFBUT<10 s (p =
0.066). In logistic regression analysis, atopy was found to be the
determinant of lower TFBUT (OR = 16.33, 95%; CI = 1.17 to 228.05, p= 0.03).
CONCLUSION: The presence of tear film instability was higher in children
with AC, AR and asthma. This finding should be taken in consideration
in atopic children.
Dogru M, Gunay M, Celik G, Aktas A. Cutan Ocul Toxicol. 2015 Feb 19:1-4.
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