It has been speculated for a long time that a medication that treats acne called 13-cis retinoic acid (RA) – commercially known as "Accutane", causes dry eyes in young adults. This dry eye syndrome is one of the most difficult to treat. By this time, eyes are constantly irritated, can’t wear contact lenses, eye drops do not help.
Studies show the key ingredients RA is also in anti-aging creams to be used around the eyes, which maybe causing Meibomina Gland Dynsfunction.
A group of researchers at Ohio State University looked at the effect of RA in various dosages and at different time points to cell viability (cellular health and levels of activities). They showed RA inhibited cell proliferation (growth), increased cell death, altered gene- expression ( could cause cancer), and promoted inflammatory mediators and protease expression in meibomian gland epithelial cells. Basically the meibomian gland cells are also tuned down at the same time to stop acne formation on the skin.
This is an abstract from IOVS June 2013 54:4341-4350; published ahead of print May 30, 2013, Ohio State University, Columbus, OH
The use of TheraLife Eye plus hot compress, eye lid cleaning and Omega 3 Fish Oil can revitalize meibomian glands intra-cellulary and relief dry eyes.
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